Across TCGA patient cohorts, H2BC12 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible H2BC12-associated genes across cancer lineages are RNU2-57P, MIR1283-2, and RNU6-996P. Each is linked with H2BC12 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2BC12-to-partner and partner-to-H2BC12 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC12→partner) and Y-score (partner→H2BC12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU2-57P →	+0.167	+8.055	<.001	.007	3	1
COAD	MIR1283-2 →	+0.392	+7.741	<.001	.009	3	1
BRCA	RNU6-996P →	+0.424	+9.057	<.001	.003	3	1
BRCA	RNU6-847P →	+0.277	+8.055	<.001	.007	3	1
BRCA	RNF19BPY →	+0.024	+9.057	<.001	.003	3	1
BRCA	RAB9AP1 →	+0.059	+9.057	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

H2BC12 survival (RNA) · tumor vs normal (RNA) · all H2BC12 data types