H2BC11

Across TCGA pan-cancer cohorts, H2BC11 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated H2BC11 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher H2BC11 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated H2BC11 expression acts as an unfavorable survival marker.

SKCM and BRCA are the cancer types where H2BC11 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Median	III,IV	0.202	0.705	.006	8	view →
BRCA	DFS	Median	All	0.150	0.526	.032	4	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

H2BC11–SKCM (OS)

Open the SKCM breakdown →