H2BC11

Across TCGA cell cohorts, H2BC11 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,807 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible H2BC11-associated GO terms across cancer lineages are Protein localization to CENP-A containing chromatin, Regulation of tumor necrosis factor-mediated signaling pathway, and Latent virus replication. Each is linked with H2BC11 in more than 13 cancer types. Because this analysis shows association rather than direction, both H2BC11-to-partner and partner-to-H2BC11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to CENP-A containing chromatin grouped by H2BC11-low versus H2BC11-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC11→partner) and Y-score (partner→H2BC11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Protein localization to CENP-A containing chromatin →	+0.374	+1.379	.001	<.001	3	14
BONE	Regulation of tumor necrosis factor-mediated signaling pathway →	+0.087	+1.873	<.001	.001	3	11
LUNG_SCLC	Latent virus replication →	+0.148	+1.319	<.001	<.001	3	9
LUNG_SCLC	Release from viral latency →	+0.148	+1.319	<.001	<.001	3	9
PANCREAS	Chromosome condensation →	+0.140	+1.532	.001	.001	3	8
PANCREAS	Protein depolymerization →	+0.095	+1.477	.003	<.001	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,807 associations by consensus.

Protein localization to CENP-A containing chromatin by H2BC11 expression — BREAST

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