H2BC10

Across TCGA patient cohorts, H2BC10 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,823 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible H2BC10-associated proteins across cancer lineages are MKI67_S2528, NCAPD2, and NCL_T121. Each is linked with H2BC10 in more than 5 cancer types. Because this analysis shows association rather than direction, both H2BC10-to-partner and partner-to-H2BC10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, H2BC10 versus MKI67_S2528 in CCRCC, with a Pearson correlation of 0.54.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC10→partner) and Y-score (partner→H2BC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MKI67_S2528 →	+1.219	+1.117	<.001	<.001	3	6
CCRCC	NCAPD2 →	+0.688	+1.065	.003	<.001	3	5
LSCC	NCL_T121 →	+1.240	+1.095	<.001	.002	3	5
LUAD	SAMHD1_T592 →	+0.817	+1.076	<.001	<.001	3	5
LUAD	BRCA1_S114 →	+0.976	+0.964	<.001	<.001	3	5
GBM	DNMT1 →	+0.348	+0.929	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,823 associations by consensus.

H2BC10 vs MKI67_S2528 — CCRCC

Explore this scatter interactively →