H2BC10

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, H2BC10 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible H2BC10-associated genes across cancer lineages are VSIG4. Each is linked with H2BC10 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2BC10-to-partner and partner-to-H2BC10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VSIG4 grouped by H2BC10-low versus H2BC10-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2BC10→partner) and Y-score (partner→H2BC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_SCLCVSIG4 →+0.023+5.029<.001.00631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

VSIG4 by H2BC10 expression — LUNG_SCLC

Box plot of VSIG4 in H2BC10-low vs H2BC10-high samples in LUNG_SCLC.

Explore this box plot interactively →

Exploration