H2AZP6

Across TCGA pan-cancer cohorts, H2AZP6 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of H2AZP6’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where H2AZP6 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types H2AZP6 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

STAD, KICH, and ESCA are the cancer types where H2AZP6 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in H2AZP6 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	All	II,III,IV	+0.338	<.001	7	view →
KICH	All	All	−0.070	.021	3	view →
ESCA	All	II,III,IV	+0.410	.038	2	view →
THCA	All	All	−0.049	.020	1	view →
HNSC	All	II,III,IV	−0.048	.047	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

H2AZP6–STAD

Open the STAD breakdown →