Across TCGA pan-cancer cohorts, H2ACP2 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of H2ACP2’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where H2ACP2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types H2ACP2 is over-expressed in tumor.

HNSC and LUSC are the cancer types where H2ACP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in H2ACP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	III,IV	+0.116	.018	5	view →
LUSC	All	All	+0.055	.019	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: H2ACP2 RNA expression & survival · all H2ACP2 data types