Across TCGA patient cohorts, H2AC7 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,059 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible H2AC7-associated GO terms across cancer lineages are Protein localization to CENP-A containing chromatin, Protein localization to chromosome, centromeric region, and Innate immune response in mucosa. Each is linked with H2AC7 in more than 32 cancer types. Because this analysis shows association rather than direction, both H2AC7-to-partner and partner-to-H2AC7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC7→partner) and Y-score (partner→H2AC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Protein localization to CENP-A containing chromatin →	+0.852	+0.948	.007	.002	1	33
ESCA	Protein localization to chromosome, centromeric region →	+0.068	+1.005	<.001	<.001	2	26
TGCT	Innate immune response in mucosa →	+0.114	+1.791	<.001	<.001	3	23
SCLC	Organ or tissue specific immune response →	+0.153	+0.716	.001	.009	1	25
TGCT	Protein localization to chromatin →	+0.047	+1.275	<.001	<.001	3	22
LAML	Negative regulation of megakaryocyte differentiation →	+0.077	+1.636	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,059 associations by consensus.

Exploration

H2AC7 survival (RNA) · tumor vs normal (RNA) · all H2AC7 data types