Across TCGA patient cohorts, H2AC7 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible H2AC7-associated genes across cancer lineages are MIR412, MIR4456, and MIR3135B. Each is linked with H2AC7 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2AC7-to-partner and partner-to-H2AC7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC7→partner) and Y-score (partner→H2AC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MIR412 →	+0.461	+7.741	<.001	.009	3	1
COAD	MIR4456 →	+0.761	+7.741	<.001	.009	3	1
UCEC	MIR3135B →	+0.671	+4.621	<.001	.008	3	1
UCEC	MIR4672 →	+0.782	+4.211	.001	.009	3	1
LUSC	OR1A2 →	+0.072	+6.438	.009	.001	3	1
LUSC	RNU6-670P →	+0.495	+5.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration

H2AC7 survival (RNA) · tumor vs normal (RNA) · all H2AC7 data types