Across TCGA pan-cancer cohorts, H2AC21 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated H2AC21 data layer compared with 23 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher H2AC21 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated H2AC21 expression acts as an unfavorable survival marker.

COAD are the cancer types where H2AC21 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	0.140	0.783	<.001	18	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: H2AC21 tumor-vs-normal RNA expression · all H2AC21 data types