Across TCGA patient cohorts, H2AC21 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,707 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H2AC21-associated proteins across cancer lineages are LIN54_S635, NSD2, and MCM2_S139. Each is linked with H2AC21 in more than 7 cancer types. Because this analysis shows association rather than direction, both H2AC21-to-partner and partner-to-H2AC21 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC21→partner) and Y-score (partner→H2AC21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LIN54_S635 →	+0.692	+0.938	<.001	<.001	3	8
COAD	NSD2 →	+0.553	+0.353	.001	.009	3	7
LUAD	MCM2_S139 →	+0.831	+0.685	<.001	<.001	3	7
LUAD	MCM2_S41 →	+0.641	+0.665	<.001	<.001	3	7
GBM	MCM5 →	+0.691	+1.023	<.001	<.001	3	7
LUAD	MKI67_S2528 →	+1.694	+0.959	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,707 associations by consensus.

Exploration

H2AC21 survival (RNA) · tumor vs normal (RNA) · all H2AC21 data types