Across TCGA patient cohorts, H2AC21 protein abundance is significantly associated with the protein abundance of many other proteins, with 22,846 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible H2AC21-associated proteins across cancer lineages are ZNF22, HIRIP3_S530, and BUB3. Each is linked with H2AC21 in more than 6 cancer types. Because this analysis shows association rather than direction, both H2AC21-to-partner and partner-to-H2AC21 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC21→partner) and Y-score (partner→H2AC21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ZNF22 →	+0.477	+0.331	<.001	<.001	3	7
LSCC	HIRIP3_S530 →	+0.677	+0.477	<.001	<.001	3	7
GBM	BUB3 →	+0.310	+0.431	<.001	<.001	3	6
BRCA	FOXO4_S241 →	+0.947	+0.452	<.001	.009	2	7
HNSC	GABPB1 →	+0.505	+0.638	<.001	<.001	3	6
GBM	H1-10 →	+0.716	+0.473	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,846 associations by consensus.

Exploration

H2AC21 survival (RNA) · tumor vs normal (RNA) · all H2AC21 data types