Across TCGA cell cohorts, H2AC21 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,688 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible H2AC21-associated GO terms across cancer lineages are Metaphase/anaphase transition of mitotic cell cycle, Meiotic chromosome separation, and Metaphase/anaphase transition of cell cycle. Each is linked with H2AC21 in more than 8 cancer types. Because this analysis shows association rather than direction, both H2AC21-to-partner and partner-to-H2AC21 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC21→partner) and Y-score (partner→H2AC21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Metaphase/anaphase transition of mitotic cell cycle →	+0.141	+0.298	<.001	<.001	3	9
SOFT_TISSUE	Meiotic chromosome separation →	+0.334	+0.228	.009	<.001	3	8
SOFT_TISSUE	Metaphase/anaphase transition of cell cycle →	+0.143	+0.272	<.001	<.001	3	7
SOFT_TISSUE	Kinetochore organization →	+0.118	+0.181	<.001	.008	3	7
SOFT_TISSUE	Positive regulation of nuclear division →	+0.112	+0.270	.001	<.001	3	7
SOFT_TISSUE	Leading strand elongation →	+0.140	+0.248	.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,688 associations by consensus.

Exploration

H2AC21 survival (RNA) · tumor vs normal (RNA) · all H2AC21 data types