Across TCGA patient cohorts, H2AC20 mutation is significantly associated with the RNA expression of many other genes, with 72 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible H2AC20-associated genes across cancer lineages are RNU6-264P, RNU6-1028P, and RNU6-110P. Each is linked with H2AC20 in more than 2 cancer types. Because this analysis shows association rather than direction, both H2AC20-to-partner and partner-to-H2AC20 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC20→partner) and Y-score (partner→H2AC20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	RNU6-264P →	+0.456	+5.474	<.001	.005	3	3
BRCA	RNU6-1028P →	+0.704	+4.683	<.001	.005	3	2
LIHC	RNU6-110P →	+0.310	+5.268	<.001	.006	3	2
CESC	MYF5 →	+0.053	+5.812	<.001	.003	3	2
CESC	RNU4-9P →	+0.290	+5.103	<.001	.008	3	2
HNSC	RNU4-70P →	+0.643	+7.954	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 72 associations by consensus.

Exploration

H2AC20 survival (RNA) · tumor vs normal (RNA) · all H2AC20 data types