H2AC14

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, H2AC14 mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible H2AC14-associated genes across cancer lineages are Ku80. Each is linked with H2AC14 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2AC14-to-partner and partner-to-H2AC14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by H2AC14-low versus H2AC14-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC14→partner) and Y-score (partner→H2AC14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECKu80 →+0.378+2.820.008.03631
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Ku80 by H2AC14 expression — UCEC

Box plot of Ku80 in H2AC14-low vs H2AC14-high samples in UCEC.

Explore this box plot interactively →

Exploration