H2AC1

Across TCGA patient cohorts, H2AC1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible H2AC1-associated genes across cancer lineages are CMP, Pericytes, and Erythrocytes. Each is linked with H2AC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both H2AC1-to-partner and partner-to-H2AC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CMP grouped by H2AC1-low versus H2AC1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (H2AC1→partner) and Y-score (partner→H2AC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CMP →	+0.035	+1.987	.010	.021	3	1
SKCM	Pericytes →	+0.060	+1.947	.003	.024	3	1
UCEC	Erythrocytes →	+0.044	+2.879	.002	.033	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CMP by H2AC1 expression — SKCM

Explore this box plot interactively →