Across TCGA patient cohorts, H1-2 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,782 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible H1-2-associated proteins across cancer lineages are NCAPH, POLD1, and RACGAP1. Each is linked with H1-2 in more than 6 cancer types. Because this analysis shows association rather than direction, both H1-2-to-partner and partner-to-H1-2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (H1-2→partner) and Y-score (partner→H1-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	NCAPH →	+0.726	+0.908	<.001	<.001	3	7
UCEC	POLD1 →	+0.441	+1.381	<.001	.001	3	6
LUAD	RACGAP1 →	+0.702	+0.568	<.001	<.001	3	6
LUAD	RFC1_T506 →	+1.009	+0.581	<.001	<.001	3	6
LSCC	RFC2 →	+0.485	+0.721	<.001	<.001	3	6
UCEC	RRM2 →	+0.993	+1.636	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,782 associations by consensus.

Exploration

H1-2 survival (RNA) · tumor vs normal (RNA) · all H1-2 data types