Across TCGA cell cohorts, H1-2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,835 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible H1-2-associated GO terms across cancer lineages are Protein localization to CENP-A containing chromatin, Vesicle targeting, rough ER to cis-Golgi, and Autophagosome maturation. Each is linked with H1-2 in more than 8 cancer types. Because this analysis shows association rather than direction, both H1-2-to-partner and partner-to-H1-2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (H1-2→partner) and Y-score (partner→H1-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Protein localization to CENP-A containing chromatin →	+0.247	+2.125	.005	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Vesicle targeting, rough ER to cis-Golgi →	+0.100	+1.343	<.001	<.001	2	9
UPPER_AERODIGESTIVE_TRACT	Autophagosome maturation →	+0.066	+1.242	.001	.001	3	7
STOMACH	Microtubule bundle formation →	-0.050	-2.463	<.001	<.001	3	6
BONE	'de novo' AMP biosynthetic process →	-0.122	-1.660	.003	<.001	3	6
KIDNEY	Positive regulation of cellular respiration →	+0.173	+1.565	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,835 associations by consensus.

Exploration

H1-2 survival (RNA) · tumor vs normal (RNA) · all H1-2 data types