GZMA

Across TCGA patient cohorts, GZMA RNA expression is significantly associated with the protein abundance of many other proteins, with 15,987 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GZMA-associated proteins across cancer lineages are RCSD1, SAMHD1, and SASH3. Each is linked with GZMA in more than 9 cancer types. Because this analysis shows association rather than direction, both GZMA-to-partner and partner-to-GZMA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GZMA versus RCSD1 in UCEC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GZMA→partner) and Y-score (partner→GZMA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RCSD1 →	+0.595	+1.650	<.001	<.001	3	10
UCEC	SAMHD1 →	+0.601	+1.548	<.001	<.001	3	10
UCEC	SASH3 →	+0.573	+1.405	<.001	<.001	3	10
GBM	SEPTIN1 →	+0.868	+1.087	<.001	<.001	3	10
UCEC	CORO1A →	+0.684	+1.562	<.001	<.001	3	10
OV	DEF6 →	+0.725	+2.290	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,987 associations by consensus.

GZMA vs RCSD1 — UCEC

Explore this scatter interactively →