GZMA

Across TCGA cell cohorts, GZMA mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible GZMA-associated genes across cancer lineages are IQCF3. Each is linked with GZMA in more than 1 cancer types. Because this analysis shows association rather than direction, both GZMA-to-partner and partner-to-GZMA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IQCF3 grouped by GZMA-low versus GZMA-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GZMA→partner) and Y-score (partner→GZMA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	IQCF3 →	+0.021	+5.228	.006	.005	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

IQCF3 by GZMA expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →