GZF1

Across TCGA pan-cancer cohorts, GZF1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated GZF1 data layer compared with 25 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher GZF1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated GZF1 expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

CCRCC, PDAC, and UCEC are the cancer types where GZF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.361	0.858	.001	60	view →
PDAC	DFS	Tertile	All	0.155	0.806	.024	10	view →
UCEC	DFS	Tertile	II,III,IV	0.458	1.000	.007	8	view →
GBM	OS	Quartile	All	0.513	0.267	.027	2	view →
LSCC	OS	Median	II,III,IV	0.810	1.000	.035	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

GZF1–CCRCC (DFS)

Open the CCRCC breakdown →