GZF1

Across TCGA patient cohorts, GZF1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,544 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GZF1-associated genes across cancer lineages are MSH6, HMBS, and PNPT1. Each is linked with GZF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GZF1-to-partner and partner-to-GZF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GZF1 versus MSH6 in LSCC, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GZF1→partner) and Y-score (partner→GZF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MSH6 →	+0.543	+0.210	<.001	.004	3	3
LSCC	HMBS →	+0.392	+0.203	<.001	<.001	3	3
LSCC	PNPT1 →	+0.445	+0.303	<.001	<.001	3	3
LSCC	APBA2 →	+0.756	+0.234	<.001	.002	3	3
OV	DCAF8 →	+0.648	+0.515	.001	.002	3	3
OV	DRD2 →	+1.001	+0.496	.002	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,544 associations by consensus.

GZF1 vs MSH6 — LSCC

Explore this scatter interactively →