GYS2

Across TCGA patient cohorts, GYS2 protein abundance is significantly associated with the RNA expression of many other genes, with 6,741 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GYS2-associated genes across cancer lineages are ITGA9-AS1, YPEL1, and PPM1F. Each is linked with GYS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GYS2-to-partner and partner-to-GYS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GYS2 versus ITGA9-AS1 in CCRCC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GYS2→partner) and Y-score (partner→GYS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ITGA9-AS1 →	-0.362	-0.409	.001	.008	3	2
CCRCC	YPEL1 →	-0.304	-0.458	.003	.003	3	1
CCRCC	PPM1F →	-0.518	-0.532	.001	.004	3	1
CCRCC	MFNG →	-0.405	-0.649	.007	.001	3	1
CCRCC	EFS →	-0.557	-0.515	.003	<.001	3	1
CCRCC	AHCY →	+0.300	+0.454	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,741 associations by consensus.

GYS2 vs ITGA9-AS1 — CCRCC

Explore this scatter interactively →