Across TCGA patient cohorts, GYPE RNA expression is significantly associated with the protein abundance of many other proteins, with 15,591 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GYPE-associated proteins across cancer lineages are SEPTIN4, PLAC9, and CLPX. Each is linked with GYPE in more than 6 cancer types. Because this analysis shows association rather than direction, both GYPE-to-partner and partner-to-GYPE results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GYPE→partner) and Y-score (partner→GYPE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SEPTIN4 →	+0.686	+0.938	<.001	<.001	3	7
OV	PLAC9 →	+0.888	+0.215	<.001	<.001	3	6
OV	CLPX →	-0.271	-0.304	<.001	<.001	3	6
BRCA	EEF1G →	-0.322	-0.294	<.001	<.001	3	6
PDAC	MRPS35 →	-0.367	-0.488	<.001	<.001	3	6
OV	GEM_S23 →	+1.356	+0.336	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,591 associations by consensus.

Exploration

GYPE survival (RNA) · tumor vs normal (RNA) · all GYPE data types