GYPB

Across TCGA cell cohorts, GYPB RNA expression is significantly associated with the go_rna of many other GO terms, with 1,576 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GYPB-associated GO terms across cancer lineages are Regulation of endodermal cell differentiation, Dopamine transport, and Regulation of axon extension. Each is linked with GYPB in more than 3 cancer types. Because this analysis shows association rather than direction, both GYPB-to-partner and partner-to-GYPB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of endodermal cell differentiation grouped by GYPB-low versus GYPB-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GYPB→partner) and Y-score (partner→GYPB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of endodermal cell differentiation →	+0.196	+0.157	<.001	<.001	3	4
BLOOD_Myeloma	Dopamine transport →	+1.243	+0.086	<.001	.009	3	3
BLOOD_Leukemia	Regulation of axon extension →	+0.045	+1.228	<.001	.007	3	3
BLOOD_Leukemia	Stress granule assembly →	+0.050	+1.601	<.001	<.001	3	3
BLOOD_Leukemia	snRNA transcription by RNA polymerase III →	+0.059	+1.725	<.001	.007	3	3
BLOOD_Leukemia	Prepulse inhibition →	-0.342	-3.004	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,576 associations by consensus.

Regulation of endodermal cell differentiation by GYPB expression — LUNG_SCLC

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