GYG2

Across TCGA patient cohorts, GYG2 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,622 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GYG2-associated proteins across cancer lineages are GYG2_S468, EIF5A2, and RASAL3. Each is linked with GYG2 in more than 4 cancer types. Because this analysis shows association rather than direction, both GYG2-to-partner and partner-to-GYG2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GYG2 versus GYG2_S468 in BRCA, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GYG2→partner) and Y-score (partner→GYG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GYG2_S468 →	+1.139	+1.639	<.001	<.001	3	5
OV	EIF5A2 →	+0.648	+0.813	<.001	<.001	3	5
GBM	RASAL3 →	-0.351	-1.139	.001	<.001	3	4
LSCC	AS3MT →	+0.605	+0.895	<.001	<.001	3	4
LSCC	GLIS2_S159 →	+0.577	+0.713	<.001	.001	3	4
OV	CD276 →	+0.403	+1.071	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,622 associations by consensus.

GYG2 vs GYG2_S468 — BRCA

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