GYG2-AS1

Across TCGA pan-cancer cohorts, GYG2-AS1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated GYG2-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher GYG2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GYG2-AS1 expression acts as an unfavorable survival marker, although some lineages such as OV and LIHC show a favorable association.

ACC, KICH, and UVM are the cancer types where GYG2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Tertile	All	0.135	0.667	<.001	87	view →
KICH	OS	Tertile	All	0.082	0.877	<.001	78	view →
UVM	OS	Tertile	III,IV	0.070	0.843	<.001	54	view →
READ	DFS	Tertile	All	0.216	0.602	.003	54	view →
OV	DFS	Median	III,IV	0.195	0.125	.002	52	view →
MESO	OS	Tertile	IV	0.036	0.602	<.001	36	view →
SKCM	DFS	Tertile	All	0.492	0.675	.001	33	view →
COAD	OS	Tertile	III,IV	0.178	0.700	.004	18	view →
LIHC	OS	Tertile	II,III,IV	1.000	0.592	.027	18	view →
SARC	DFS	Tertile	All	0.229	0.529	.002	18	view →
THCA	OS	Tertile	IV	0.751	1.000	.014	9	view →
KIRP	DFS	Tertile	All	0.344	0.639	.021	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

GYG2-AS1–ACC (DFS)

Open the ACC breakdown →