GYG1

Across TCGA cell cohorts, GYG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,207 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GYG1-associated GO terms across cancer lineages are Chromosomal DNA methylation maintenance following DNA replication, Synaptic vesicle lumen acidification, and Melanosome organization. Each is linked with GYG1 in more than 10 cancer types. Because this analysis shows association rather than direction, both GYG1-to-partner and partner-to-GYG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Chromosomal DNA methylation maintenance following DNA replication grouped by GYG1-low versus GYG1-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GYG1→partner) and Y-score (partner→GYG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Chromosomal DNA methylation maintenance following DNA replication →	+0.194	+1.008	<.001	.001	3	11
SOFT_TISSUE	Synaptic vesicle lumen acidification →	+0.134	+0.520	<.001	.003	3	8
SOFT_TISSUE	Melanosome organization →	+0.062	+1.063	<.001	<.001	3	7
SOFT_TISSUE	Pigment granule organization →	+0.062	+1.063	<.001	<.001	3	7
BLOOD_Leukemia	Melanosome assembly →	+0.068	+1.187	<.001	<.001	3	7
BONE	Regulation of glucose mediated signaling pathway →	-0.145	-1.937	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,207 associations by consensus.

Chromosomal DNA methylation maintenance following DNA replication by GYG1 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →