GXYLT2

Across TCGA patient cohorts, GXYLT2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,560 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GXYLT2-associated genes across cancer lineages are MYL9, COL1A1, and PRRX1. Each is linked with GXYLT2 in more than 3 cancer types. Because this analysis shows association rather than direction, both GXYLT2-to-partner and partner-to-GXYLT2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GXYLT2 versus MYL9 in LSCC, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GXYLT2→partner) and Y-score (partner→GXYLT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MYL9 →	+1.093	+0.670	.001	<.001	3	4
OV	COL1A1 →	+2.288	+0.961	<.001	<.001	3	4
HNSC	PRRX1 →	+1.248	+0.862	.001	<.001	3	4
HNSC	PLXDC2 →	+0.891	+0.896	.001	<.001	3	4
OV	COL10A1 →	+1.663	+0.689	<.001	<.001	3	4
BRCA	LOXL1 →	+1.614	+1.135	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,560 associations by consensus.

GXYLT2 vs MYL9 — LSCC

Explore this scatter interactively →