GXYLT2

Across TCGA cell cohorts, GXYLT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,139 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GXYLT2-associated GO terms across cancer lineages are Vesicle cargo loading, Collagen fibril organization, and Regulation of cell-matrix adhesion. Each is linked with GXYLT2 in more than 11 cancer types. Because this analysis shows association rather than direction, both GXYLT2-to-partner and partner-to-GXYLT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle cargo loading grouped by GXYLT2-low versus GXYLT2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GXYLT2→partner) and Y-score (partner→GXYLT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Vesicle cargo loading →	+0.143	+1.925	.001	.004	3	12
LUNG_NSCLC_LUSC	Collagen fibril organization →	+0.342	+2.115	<.001	<.001	3	11
BONE	Regulation of cell-matrix adhesion →	+0.160	+1.215	<.001	.004	3	11
LUNG_NSCLC_LUSC	Protein import into peroxisome membrane →	+0.126	+1.555	<.001	<.001	2	11
BONE	Positive regulation of stress fiber assembly →	+0.173	+1.334	<.001	<.001	3	10
OVARY	Protein folding →	+0.048	+1.125	.001	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,139 associations by consensus.

Vesicle cargo loading by GXYLT2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →