GXYLT1P6

Across TCGA pan-cancer cohorts, GXYLT1P6 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated GXYLT1P6 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher GXYLT1P6 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated GXYLT1P6 expression acts as an unfavorable survival marker, although some lineages such as GBM and BRCA show a favorable association.

DLBC, ESCA, and CHOL are the cancer types where GXYLT1P6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Tertile	II,III,IV	0.172	0.949	<.001	54	view →
ESCA	DFS	Median	IV	0.205	0.634	.006	36	view →
CHOL	OS	Tertile	III,IV	0.024	0.772	.008	36	view →
GBM	DFS	Median	All	0.433	0.173	<.001	30	view →
BRCA	OS	Tertile	IV	0.719	0.232	.021	15	view →
KIRP	DFS	Quartile	All	0.560	0.743	.004	14	view →
THYM	DFS	Median	II,III,IV	1.000	0.723	.014	13	view →
STAD	DFS	Median	IV	0.221	0.573	.024	12	view →
KIRC	DFS	Median	IV	0.476	0.182	.024	6	view →
LUAD	OS	Tertile	All	0.726	0.855	.011	6	view →
KICH	DFS	Tertile	II,III,IV	0.292	0.853	.018	5	view →
LIHC	DFS	Quartile	All	0.658	0.520	.036	4	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

GXYLT1P6–DLBC (OS)

Open the DLBC breakdown →