GXYLT1

Across TCGA cell cohorts, GXYLT1 mutation is significantly associated with the drug of many other genes, with 25 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GXYLT1-associated genes across cancer lineages are 615590, I-BRD9, and KIN001-260. Each is linked with GXYLT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GXYLT1-to-partner and partner-to-GXYLT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 615590 grouped by GXYLT1-low versus GXYLT1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GXYLT1→partner) and Y-score (partner→GXYLT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	615590 →	+0.350	+2.871	.009	.021	3	1
LARGE_INTESTINE	I-BRD9 →	+0.405	+2.649	.038	.046	3	1
LARGE_INTESTINE	KIN001-260 →	+0.415	+2.807	.020	.044	3	1
LARGE_INTESTINE	ARRY-520 →	+0.799	+2.807	.023	.044	3	1
LARGE_INTESTINE	IC-87114 →	+0.204	+2.874	.037	.021	2	1
LARGE_INTESTINE	Y-39983 →	+0.569	+2.874	.004	.021	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

615590 by GXYLT1 expression — LARGE_INTESTINE

Explore this box plot interactively →