GVINP2

Across TCGA pan-cancer cohorts, GVINP2 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated GVINP2 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher GVINP2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GVINP2 expression acts as an unfavorable survival marker, although some lineages such as SKCM and KIRC show a favorable association.

UCEC, KICH, and KIRP are the cancer types where GVINP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	All	0.752	0.859	.001	114	view →
KICH	OS	Quartile	All	0.617	0.919	<.001	97	view →
KIRP	DFS	Tertile	II,III,IV	0.116	0.649	<.001	58	view →
BRCA	OS	Tertile	All	0.451	0.666	.002	47	view →
LUSC	OS	Tertile	IV	0.001	0.651	.025	39	view →
SKCM	OS	Tertile	III,IV	0.585	0.246	<.001	27	view →
LIHC	OS	Tertile	III,IV	0.273	0.595	.006	27	view →
MESO	OS	Tertile	IV	0.229	0.647	.007	18	view →
PAAD	OS	Tertile	III,IV	0.653	0.952	.025	12	view →
OV	DFS	Tertile	II,III,IV	0.482	0.555	.038	12	view →
CHOL	OS	Tertile	All	0.164	0.770	.010	9	view →
KIRC	DFS	Quartile	All	0.744	0.582	.009	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

GVINP2–UCEC (DFS)

Open the UCEC breakdown →