GVINP1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GVINP1 protein abundance is significantly associated with the go_rna of many other GO terms, with 486 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GVINP1-associated GO terms across cancer lineages are DNA replication, removal of RNA primer, Engulfment of apoptotic cell, and Triglyceride metabolic process. Each is linked with GVINP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both GVINP1-to-partner and partner-to-GVINP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication, removal of RNA primer grouped by GVINP1-low versus GVINP1-high in BLOOD_Lymphoma.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GVINP1→partner) and Y-score (partner→GVINP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaDNA replication, removal of RNA primer →-0.123-1.338<.001.00833
LUNG_SCLCEngulfment of apoptotic cell →+0.459+1.313.001.00424
BLOOD_LymphomaTriglyceride metabolic process →-0.045-1.355.005.00733
LUNG_SCLCIntracellular magnesium ion homeostasis →+0.216+0.960.004.00624
BREASTNegative regulation of calcium ion import →+0.110+1.356.007.00233
SKINIsocitrate metabolic process →-0.131-1.429.007.00233
Each partner links to its Q-omics profile. Showing the 6 strongest of 486 associations by consensus.

DNA replication, removal of RNA primer by GVINP1 expression — BLOOD_Lymphoma

Box plot of DNA replication, removal of RNA primer in GVINP1-low vs GVINP1-high samples in BLOOD_Lymphoma.

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Exploration