Q-omics provides the consensus-scored GUSBP9 profile across patient tissues and cancer cell-line models. GUSBP9 expression is associated with patient survival in 24 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, GUSBP9 is differentially expressed in 8, with the highest sampling consensus in THCA. Additionally, GUSBP9 RNA expression shows 18,358 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight HNSC, THCA, and THYM as cancer lineages where GUSBP9 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for GUSBP9 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes GUSBP9 survival associations across molecular data types. GUSBP9 RNA expression shows survival associations in the most cancer types (24). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible GUSBP9 RNA expression–survival associations across cancer types. High GUSBP9 expression shows unfavorable associations in OV and DLBC, but favorable associations in HNSC, PAAD, KIRC and UCS. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify HNSC as the clearest survival context for GUSBP9 RNA expression.
This table summarizes GUSBP9 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for GUSBP9. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. GUSBP9 shows lower tumor expression in THCA, UCEC and KICH and higher tumor expression in CHOL, LIHC and COAD. The THCA box plot shows higher GUSBP9 RNA expression in normal versus tumor tissue (log2 FC = −0.843, t-test p < 0.001).
This table shows molecular features associated with GUSBP9 in patient tissues and cancer cell lines. In patient samples, GUSBP9 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
