Across TCGA pan-cancer cohorts, GUSBP6 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated GUSBP6 data layer.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher GUSBP6 RNA is associated with better overall survival. In most high-consensus cancer types, elevated GUSBP6 expression acts as an unfavorable survival marker, although some lineages such as HNSC and ESCA show a favorable association.
HNSC, KIRC, and LUSC are the cancer types where GUSBP6 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.