GUSBP2

Across TCGA patient cohorts, GUSBP2 mutation is significantly associated with the RNA expression of many other genes, with 365 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GUSBP2-associated genes across cancer lineages are TRADD, LACTB, and SNAPC2. Each is linked with GUSBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GUSBP2-to-partner and partner-to-GUSBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRADD grouped by GUSBP2-low versus GUSBP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GUSBP2→partner) and Y-score (partner→GUSBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRADD →	+0.713	+3.491	<.001	.002	3	1
UCEC	LACTB →	+0.539	+3.502	.004	.002	3	1
UCEC	SNAPC2 →	+0.746	+3.470	<.001	.003	3	1
UCEC	BBC3 →	+0.753	+3.338	.002	.005	3	1
UCEC	KXD1 →	+0.461	+3.491	.003	.002	3	1
UCEC	STAG3L4 →	+0.696	+3.459	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 365 associations by consensus.

TRADD by GUSBP2 expression — UCEC

Explore this box plot interactively →