Across TCGA pan-cancer cohorts, GUSBP16 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of GUSBP16’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where GUSBP16 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GUSBP16 is over-expressed in tumor.
LUAD are the cancer types where GUSBP16 tumor–normal differential expression is most reproducible.