GUSBP12

Across TCGA pan-cancer cohorts, GUSBP12 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated GUSBP12 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher GUSBP12 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated GUSBP12 expression acts as an unfavorable survival marker, although some lineages such as UCS and KIRC show a favorable association.

UCS, KICH, and KIRC are the cancer types where GUSBP12 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Median	II,III,IV	0.619	0.150	<.001	72	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	36	view →
KIRC	DFS	Tertile	II,III,IV	0.920	0.509	.019	30	view →
COAD	OS	Tertile	IV	0.039	0.660	<.001	27	view →
PCPG	OS	Tertile	All	0.670	0.946	.001	21	view →
KIRP	DFS	Tertile	II,III,IV	0.519	0.783	<.001	15	view →
HNSC	OS	Tertile	III,IV	0.566	0.754	.019	12	view →
SARC	OS	Tertile	All	0.628	0.843	.004	9	view →
CHOL	OS	Tertile	All	0.155	0.725	.029	9	view →
SKCM	OS	Tertile	II,III,IV	0.184	0.401	.047	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

GUSBP12–UCS (DFS)

Open the UCS breakdown →