Across TCGA patient cohorts, GUSBP1 mutation is significantly associated with the total protein of many other genes, with 13 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GUSBP1-associated genes across cancer lineages are FOXO3a_pS318_S321, JNK_pT183_Y185, and STAT3_pY705. Each is linked with GUSBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GUSBP1-to-partner and partner-to-GUSBP1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GUSBP1→partner) and Y-score (partner→GUSBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXO3a_pS318_S321 →	-0.196	-2.990	.006	.036	3	1
UCEC	JNK_pT183_Y185 →	-0.194	-2.986	.047	.037	3	1
UCEC	STAT3_pY705 →	-0.533	-3.000	<.001	.037	3	1
UCEC	Stathmin →	+0.164	+3.000	.039	.037	3	1
UCEC	4E-BP1_pT37_T46 →	-0.503	-3.000	.020	.037	3	1
UCEC	Cyclin-B1 →	+0.655	+3.000	.043	.037	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

GUSBP1 survival (RNA) · tumor vs normal (RNA) · all GUSBP1 data types