GUSB

Across TCGA patient cohorts, GUSB protein abundance is significantly associated with the protein abundance of many other proteins, with 16,356 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GUSB-associated proteins across cancer lineages are SUMF2, CD63, and SDF4. Each is linked with GUSB in more than 5 cancer types. Because this analysis shows association rather than direction, both GUSB-to-partner and partner-to-GUSB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GUSB versus SUMF2 in LUAD, with a Pearson correlation of 0.50.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GUSB→partner) and Y-score (partner→GUSB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	SUMF2 →	+0.403	+0.327	<.001	<.001	3	6
GBM	CD63 →	+0.640	+0.926	<.001	<.001	3	5
GBM	SDF4 →	+0.504	+1.059	<.001	<.001	3	5
GBM	SGSH →	+0.478	+1.068	<.001	<.001	3	5
LUAD	HEXA →	+0.327	+0.363	.002	.001	2	6
BRCA	SIAE →	+0.560	+0.567	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,356 associations by consensus.

GUSB vs SUMF2 — LUAD

Explore this scatter interactively →