GULP1

Across TCGA pan-cancer cohorts, GULP1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated GULP1 data layer compared with 26 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher GULP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated GULP1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

PDAC, HNSC, and UCEC are the cancer types where GULP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	III,IV	1.000	0.160	.006	19	view →
HNSC	DFS	Median	All	0.993	0.911	.007	5	view →
UCEC	DFS	Median	III,IV	0.445	0.904	.037	4	view →
CCRCC	DFS	Quartile	III,IV	0.233	0.887	.038	3	view →
GBM	OS	Median	All	0.449	0.298	.028	2	view →
LUAD	DFS	Quartile	II,III,IV	0.742	1.000	.022	1	view →
LSCC	DFS	Quartile	III,IV	0.774	1.000	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

GULP1–PDAC (DFS)

Open the PDAC breakdown →