GUF1

Across TCGA patient cohorts, GUF1 protein abundance is significantly associated with the RNA expression of many other genes, with 6,135 significant associations in total. COAD shows the largest number of these associations.

The most reproducible GUF1-associated genes across cancer lineages are FKBP14, GRPEL1, and COX6A1. Each is linked with GUF1 in more than 3 cancer types. Because this analysis shows association rather than direction, both GUF1-to-partner and partner-to-GUF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GUF1 versus FKBP14 in OV, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GUF1→partner) and Y-score (partner→GUF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FKBP14 →	-0.923	-0.370	<.001	.001	3	3
OV	GRPEL1 →	+0.595	+0.331	<.001	.002	3	3
OV	COX6A1 →	+0.825	+0.394	<.001	<.001	3	3
OV	PAICS →	+0.611	+0.413	<.001	<.001	3	3
OV	PXDN →	-1.152	-0.298	.004	.002	3	3
OV	SLC30A9 →	+0.520	+0.400	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,135 associations by consensus.

GUF1 vs FKBP14 — OV

Explore this scatter interactively →