GUF1

Across TCGA cell cohorts, GUF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,244 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GUF1-associated GO terms across cancer lineages are 'de novo' IMP biosynthetic process, Regulation of chromosome condensation, and Ribosomal large subunit export from nucleus. Each is linked with GUF1 in more than 13 cancer types. Because this analysis shows association rather than direction, both GUF1-to-partner and partner-to-GUF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 'de novo' IMP biosynthetic process grouped by GUF1-low versus GUF1-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GUF1→partner) and Y-score (partner→GUF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	'de novo' IMP biosynthetic process →	+0.141	+0.740	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of chromosome condensation →	+0.159	+1.144	<.001	<.001	3	14
OVARY	Ribosomal large subunit export from nucleus →	+0.117	+0.784	<.001	.001	3	13
BLOOD_Lymphoma	Positive regulation of chromosome condensation →	+0.176	+0.800	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Anaphase-promoting complex-dependent catabolic process →	+0.097	+1.162	<.001	<.001	3	11
CNS	RNA methylation →	+0.060	+0.531	<.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,244 associations by consensus.

'de novo' IMP biosynthetic process by GUF1 expression — OVARY

Explore this box plot interactively →