GUCY2F

Across TCGA patient cohorts, GUCY2F protein abundance is significantly associated with the RNA expression of many other genes, with 643 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GUCY2F-associated genes across cancer lineages are PCNX1, BDKRB1, and NDRG3. Each is linked with GUCY2F in more than 1 cancer types. Because this analysis shows association rather than direction, both GUCY2F-to-partner and partner-to-GUCY2F results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GUCY2F versus PCNX1 in GBM, with a Pearson correlation of -0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCY2F→partner) and Y-score (partner→GUCY2F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PCNX1 →	-0.419	-0.544	<.001	.006	3	1
GBM	BDKRB1 →	-0.389	-0.588	.003	.002	3	1
GBM	NDRG3 →	+0.383	+0.461	.006	.005	3	1
GBM	SALL4 →	-0.675	-0.635	.008	.001	3	1
GBM	MROH8 →	+0.409	+0.448	.005	.007	3	1
GBM	AHCY →	-0.391	-0.515	.006	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 643 associations by consensus.

GUCY2F vs PCNX1 — GBM

Explore this scatter interactively →