GUCY2F

Across TCGA cell cohorts, GUCY2F RNA expression is significantly associated with the go_rna of many other GO terms, with 786 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GUCY2F-associated GO terms across cancer lineages are Protein targeting to ER, ER-nucleus signaling pathway, and Ventricular cardiac muscle cell action potential. Each is linked with GUCY2F in more than 4 cancer types. Because this analysis shows association rather than direction, both GUCY2F-to-partner and partner-to-GUCY2F results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein targeting to ER grouped by GUCY2F-low versus GUCY2F-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCY2F→partner) and Y-score (partner→GUCY2F) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Protein targeting to ER →	+0.059	+0.031	.007	.007	3	5
BLOOD_Lymphoma	ER-nucleus signaling pathway →	+0.062	+0.026	<.001	.003	3	4
LARGE_INTESTINE	Ventricular cardiac muscle cell action potential →	-0.161	-0.004	.001	.006	3	4
CNS	Negative regulation of regulatory T cell differentiation →	+0.084	+0.019	.001	.001	3	4
OVARY	Regulation of DNA-templated transcription elongation →	+0.051	+0.003	.002	.006	2	5
BLOOD_Lymphoma	Establishment of protein localization to plasma membrane →	+0.057	+0.018	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 786 associations by consensus.

Protein targeting to ER by GUCY2F expression — BLOOD_Lymphoma

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