GUCY1B2

Across TCGA patient cohorts, GUCY1B2 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,638 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GUCY1B2-associated proteins across cancer lineages are ZBTB33, VDR, and SEPTIN9. Each is linked with GUCY1B2 in more than 2 cancer types. Because this analysis shows association rather than direction, both GUCY1B2-to-partner and partner-to-GUCY1B2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GUCY1B2 versus ZBTB33 in OV, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCY1B2→partner) and Y-score (partner→GUCY1B2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	ZBTB33 →	+0.372	+0.790	.006	.008	3	3
HNSC	VDR →	-0.349	-0.582	.005	.005	3	3
COAD	SEPTIN9 →	-0.174	-0.563	<.001	.009	3	3
OV	TBC1D4_S600 →	-1.346	-1.573	.001	<.001	3	3
HNSC	HNRNPU →	+0.214	+1.032	<.001	<.001	3	3
LSCC	IARS2 →	+0.345	+0.971	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,638 associations by consensus.

GUCY1B2 vs ZBTB33 — OV

Explore this scatter interactively →