GUCY1A2

Across TCGA patient cohorts, GUCY1A2 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,957 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GUCY1A2-associated proteins across cancer lineages are GUCY1B1, JCAD, and PDGFRB. Each is linked with GUCY1A2 in more than 7 cancer types. Because this analysis shows association rather than direction, both GUCY1A2-to-partner and partner-to-GUCY1A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GUCY1A2 versus GUCY1B1 in UCEC, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCY1A2→partner) and Y-score (partner→GUCY1A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GUCY1B1 →	+0.576	+1.575	<.001	<.001	3	8
UCEC	JCAD →	+0.469	+1.144	<.001	<.001	3	8
LSCC	PDGFRB →	+0.561	+1.033	<.001	<.001	3	8
BRCA	PHLDB1 →	+0.447	+0.894	<.001	<.001	3	8
OV	CLPX →	-0.256	-0.905	.001	<.001	3	8
CCRCC	COL3A1 →	+0.967	+0.997	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,957 associations by consensus.

GUCY1A2 vs GUCY1B1 — UCEC

Explore this scatter interactively →