GUCY1A2

Across TCGA patient cohorts, GUCY1A2 protein abundance is significantly associated with the RNA expression of many other genes, with 14,922 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GUCY1A2-associated genes across cancer lineages are EMCN, CALCRL, and FHL5. Each is linked with GUCY1A2 in more than 7 cancer types. Because this analysis shows association rather than direction, both GUCY1A2-to-partner and partner-to-GUCY1A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GUCY1A2 versus EMCN in CCRCC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCY1A2→partner) and Y-score (partner→GUCY1A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	EMCN →	+1.044	+0.305	<.001	<.001	3	8
GBM	CALCRL →	+0.820	+0.296	<.001	<.001	3	8
UCEC	FHL5 →	+0.988	+0.555	<.001	.001	3	7
CCRCC	MYCT1 →	+0.909	+0.303	<.001	<.001	3	7
UCEC	RHOJ →	+0.981	+0.574	<.001	<.001	3	7
CCRCC	ERG →	+0.939	+0.411	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,922 associations by consensus.

GUCY1A2 vs EMCN — CCRCC

Explore this scatter interactively →