GUCY1A2

Across TCGA cell cohorts, GUCY1A2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,307 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GUCY1A2-associated GO terms across cancer lineages are Regulation of heart contraction, Positive regulation of neutrophil chemotaxis, and Positive regulation of double-strand break repair. Each is linked with GUCY1A2 in more than 7 cancer types. Because this analysis shows association rather than direction, both GUCY1A2-to-partner and partner-to-GUCY1A2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of heart contraction grouped by GUCY1A2-low versus GUCY1A2-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GUCY1A2→partner) and Y-score (partner→GUCY1A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Regulation of heart contraction →	-0.088	-0.552	<.001	.001	2	8
BONE	Positive regulation of neutrophil chemotaxis →	-0.136	-0.662	.007	.009	3	6
SKIN	Positive regulation of double-strand break repair →	+0.038	+0.521	.003	.006	2	7
LUNG_NSCLC_LUSC	Regulation of heart rate by cardiac conduction →	-0.223	-0.548	<.001	.007	3	6
SOFT_TISSUE	Cardiac neural crest cell differentiation involved in heart development →	-0.166	-0.633	.007	.004	3	5
SOFT_TISSUE	Cardiac neural crest cell development involved in heart development →	-0.166	-0.633	.007	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,307 associations by consensus.

Regulation of heart contraction by GUCY1A2 expression — SKIN

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